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Each episode of the Physiological Reviews podcast features commentary and discussion of newly published articles in the journal, which provides state-of-the-art, comprehensive, and high-impact coverage of timely issues in the physiological and biomedical sciences. Physiological Reviews articles appeal to physiologists, neuroscientists, cell biologists, biophysicists, and clinicians with special interest in pathophysiology. The journal is very useful in teaching and research because it provides non-biased and clearly written updates on important developments.
Episodes

Friday Sep 12, 2025
Immunotherapy for Atherosclerosis
Friday Sep 12, 2025
Friday Sep 12, 2025
What role does inflammation play in atherosclerosis? In our latest episode of The Physiological Reviews Podcast, Dr. Carol Ann Remme talks with authors Dr. Esther Lutgens (Mayo Clinic) and Dr. Claudia Monaco (University of Oxford) about their recent Review on immunotherapy for atherosclerosis. The authors discuss the network of multiple immune cell types and subsets of the innate and adaptive immune system that occupy arteries. In addition, Monaco et al. discuss local inflammation in the arterial wall or plaque compared to systemic inflammation. The authors also discuss atherosclerosis as a process of aging, rather than as a disease. What is the holy grail of safe immunotherapeutic approaches and the future of personalized medicine for atherosclerosis? Listen now to learn more.
Claudia Monaco, Coleen A. McNamara, Bram Slütter, Amanda C. Foks, Stefan Bekiranov, Willem J.M. Mulder, Isabel Gonçalves, and Esther Lutgens Immunotherapy for atherosclerosis Physiological Reviews, published May 21, 2025. DOI: 10.1152/physrev.00016.2024
