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Each episode of the Physiological Reviews podcast features commentary and discussion of newly published articles in the journal, which provides state-of-the-art, comprehensive, and high-impact coverage of timely issues in the physiological and biomedical sciences. Physiological Reviews articles appeal to physiologists, neuroscientists, cell biologists, biophysicists, and clinicians with special interest in pathophysiology. The journal is very useful in teaching and research because it provides non-biased and clearly written updates on important developments.
Episodes
Thursday Feb 02, 2023
Thursday Feb 02, 2023
Physiological Reviews Associate Editor Prof. Christoph Handschin speaks with Prof. Paul L. Greenhaff and Prof. Janet M. Lord about their article “Multisystem Physiological Perspective of Human Frailty and Its Modulation by Physical Activity,” published in the April 2023 issue of Physiological Reviews.
Prof. Greenhaff is Professor at the School of Life Sciences at the University of Nottingham and is deputy director of the Medical Research Council (MRC)-Versus Arthritis Centre for Musculoskeletal Ageing Research.
Prof. Lord is Professor at the Institute of Inflammation and Ageing at the University of Birmingham and is the director of the MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research.
- Introduction of the authors [1:06]
- What does the term ‘frailty’ actually mean, and how is it clinically defined? [2:49]
- Are there specific risk factors that increase the chance of becoming frail? [5:18]
- What interventions are useful to guard against frailty? [6:55]
- How important will mechanistic aspects of frailty be in our understanding and treatment of frailty? [13:55]
- Are there things we can do with regard to prevention, the mindset of patients and physicians, and interventions in the clinic? [21:10]
- What advice do the authors have to minimize the impact of frailty, regardless of age? [23:15]
- The importance of remaining mentally active [25:55]
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